diff --git a/include/jemalloc/internal/tsd.h b/include/jemalloc/internal/tsd.h
index 2355f9c6..5df5f673 100644
--- a/include/jemalloc/internal/tsd.h
+++ b/include/jemalloc/internal/tsd.h
@@ -226,7 +226,8 @@ a_name##tsd_set(a_type *val)						\
 {									\
 									\
 	assert(a_name##tsd_booted);					\
-	a_name##tsd_tls = (*val);					\
+	if (likely(&a_name##tsd_tls != val))				\
+		a_name##tsd_tls = (*val);				\
 	if (a_cleanup != malloc_tsd_no_cleanup)				\
 		a_name##tsd_initialized = true;				\
 }
@@ -277,7 +278,8 @@ a_name##tsd_set(a_type *val)						\
 {									\
 									\
 	assert(a_name##tsd_booted);					\
-	a_name##tsd_tls = (*val);					\
+	if (likely(&a_name##tsd_tls != val))				\
+		a_name##tsd_tls = (*val);				\
 	if (a_cleanup != malloc_tsd_no_cleanup) {			\
 		if (pthread_setspecific(a_name##tsd_tsd,		\
 		    (void *)(&a_name##tsd_tls))) {			\
@@ -409,7 +411,8 @@ a_name##tsd_set(a_type *val)						\
 									\
 	assert(a_name##tsd_booted);					\
 	wrapper = a_name##tsd_wrapper_get();				\
-	wrapper->val = *(val);						\
+	if (likely(&wrapper->val != val))				\
+		wrapper->val = *(val);					\
 	if (a_cleanup != malloc_tsd_no_cleanup)				\
 		wrapper->initialized = true;				\
 }
@@ -537,7 +540,8 @@ a_name##tsd_set(a_type *val)						\
 									\
 	assert(a_name##tsd_booted);					\
 	wrapper = a_name##tsd_wrapper_get();				\
-	wrapper->val = *(val);						\
+	if (likely(&wrapper->val != val))				\
+		wrapper->val = *(val);					\
 	if (a_cleanup != malloc_tsd_no_cleanup)				\
 		wrapper->initialized = true;				\
 }