diff --git a/configure.ac b/configure.ac
index 3837a786..d5c663eb 100644
--- a/configure.ac
+++ b/configure.ac
@@ -150,6 +150,11 @@ if test "x$EXTRA_CFLAGS" != "x" ; then
 fi
 AC_PROG_CPP
 
+AC_C_BIGENDIAN([ac_cv_big_endian=1], [ac_cv_big_endian=0])
+if test "x${ac_cv_big_endian}" = "x1" ; then
+  AC_DEFINE_UNQUOTED([JEMALLOC_BIG_ENDIAN], [ ])
+fi
+
 AC_CHECK_SIZEOF([void *])
 if test "x${ac_cv_sizeof_void_p}" = "x8" ; then
   LG_SIZEOF_PTR=3
diff --git a/include/jemalloc/internal/hash.h b/include/jemalloc/internal/hash.h
index 09b69df5..c7183ede 100644
--- a/include/jemalloc/internal/hash.h
+++ b/include/jemalloc/internal/hash.h
@@ -320,7 +320,7 @@ hash_x64_128(const void *key, const int len, const uint32_t seed,
 JEMALLOC_INLINE void
 hash(const void *key, size_t len, const uint32_t seed, size_t r_hash[2])
 {
-#if (LG_SIZEOF_PTR == 3)
+#if (LG_SIZEOF_PTR == 3 && !defined(JEMALLOC_BIG_ENDIAN))
 	hash_x64_128(key, len, seed, (uint64_t *)r_hash);
 #else
 	uint64_t hashes[2];
diff --git a/include/jemalloc/internal/jemalloc_internal_defs.h.in b/include/jemalloc/internal/jemalloc_internal_defs.h.in
index e3758e47..c166fbd9 100644
--- a/include/jemalloc/internal/jemalloc_internal_defs.h.in
+++ b/include/jemalloc/internal/jemalloc_internal_defs.h.in
@@ -190,6 +190,9 @@
 /* C99 restrict keyword supported. */
 #undef JEMALLOC_HAS_RESTRICT
 
+/* For use by hash code. */
+#undef JEMALLOC_BIG_ENDIAN
+
 /* sizeof(int) == 2^LG_SIZEOF_INT. */
 #undef LG_SIZEOF_INT
 
diff --git a/test/unit/hash.c b/test/unit/hash.c
index 0446e524..abb394ac 100644
--- a/test/unit/hash.c
+++ b/test/unit/hash.c
@@ -122,9 +122,15 @@ hash_variant_verify(hash_variant_t variant)
 	    (final[3] << 24);
 
 	switch (variant) {
+#ifdef JEMALLOC_BIG_ENDIAN
+	case hash_variant_x86_32: expected = 0x6213303eU; break;
+	case hash_variant_x86_128: expected = 0x266820caU; break;
+	case hash_variant_x64_128: expected = 0xcc622b6fU; break;
+#else
 	case hash_variant_x86_32: expected = 0xb0f57ee3U; break;
 	case hash_variant_x86_128: expected = 0xb3ece62aU; break;
 	case hash_variant_x64_128: expected = 0x6384ba69U; break;
+#endif
 	default: not_reached();
 	}